In addition, the spectrum of manifestations is wide. If Klinefelter syndrome is detected in early ages, ethically considered intervention strategies may reduce the risk of later development of schizophrenia and bipolar disorder. Vulnerability for psychopathology in Klinefelter syndrome: age-specific and cognitive-specific risk profiles. Klinefelter's syndrome, characterised by a 47, XXY chromosomal pattern, has largely been associated with physical abnormalities. Most males have one Y and one X chromosome. This study is the first to access the influence of CAG length, X‐chromosome inactivation pattern and parental origin of the supernumerary X‐chromosome on psychological traits, personality traits and regional and global brain volumes in KS patients. Furthermore, they found no difference regarding education, personality and autism traits, psychological distress and socioeconomic factors (Skakkebaek et al. If you have just received a diagnosis of Klinefelter’s Syndrome for your child or unborn baby you will find help and information in our Children’s area. Loading... WHAT ARE THE CHALLENGES WE FACE? The aim of our study was to investigate fluid intelligence, personality traits and personality disorders (PD) and possible correlations with testosterone in a cohort of adult KS patients. Most variants of Klinefelter syndrome are much rarer, occurring in 1 in 50,000 or fewer newborns. Klinefelter syndrome, also known as XXY syndrome, is a condition in boys and men that’s caused by an extra X chromosome. Klinefelter syndrome may adversely affect testicular growth, resulting in smaller than normal testicles, which can lead to lower production of testosterone. Therefore, the impact of the inheritance pattern of the supernumerary X‐chromosome in men with KS remains to be unclear. Further, we analyzed personality traits and coping strategies, an issue not yet examined in androgen-treated KS patients. Personalities in this group are as varied as in the general population. METHODS: We analyzed 58 adult KS patients with the classic 47, XXY karyotype. Moreover, our data suggests a causal role of X chromosomal abnormalities in the liability to schizophrenia, bipolar disorder, autism spectrum disorders and ADHD, a role that should be investigated further. Klinefelter syndrome (KS), 47,XXY, occurs in 150 per 100,000 live born males ().No universal agreement exists in the scientific community on the exact definition of KS, but in addition to possessing one or more extra X chromosomes, KS males typically exhibit phenotypical traits that include hypergonadotropic hypogonadism, testosterone deficiency, and infertility (). Also, at the 12th IAAF World Athletic Championships in Berlin, Caster won the 800m race in a best personal time of 1.55.45 seconds. it would depend on your personality. Klinefelter syndrome occurs when a boy is born with one or more extra X chromosomes. Klinefelter syndrome (XXY) This leaflet explains what Klinefelter Syndrome is, the symptoms and treatment options. Some of the symptoms include less facial hair than is normal, broader hips that are typical of women, larger breast than other males, weaker bones and lower energy levels as compared to other males. Positive Traits; Education; Careers and Jobs; Testosterone; Ways To Give. 2014). Membership Join here . Related ArticlesHypersexuality, Paraphilic Behaviors, and Gender Dysphoria in Individuals with Klinefelter's Syndrome. Traditionally, men with KS have been described as tall, slim, narrow shouldered, broad hipped, with hypergonadotrophic hypogonadism and small testes. Male physical traits such as facial hair, a deep voice and other secondary sex characteristics are less pronounced, and libido may be reduced. Boys with Klinefelter syndrome may also have difficulty fitting in socially and interacting with their peers as personality traits often include being shy and quiet. Having extra X chromosomes can cause a male to have a variety of physical traits. Klinefelter's syndrome (KS) is the most common sex-chromosome disorder in men, affecting approximately 1:660 men, and is a rather common cause of infertility, hypogonadism and learning disability. Design Register-based cohort study comparing the incidence of convictions among men with KS and with 47,XYY with age- and calendar-matched samples of the general population. The majority seem to be the injections and the Gel. PURPOSE: Klinefelter's syndrome (KS) is associated with specific neurobehavioral features and personality traits. The question naturally arises whether the personality in Klinefelter's syndrome is particularly prone to lead to sexually deviant behavior. It is also common for men affected by Klinefelter syndrome to experience breast enlargement (gynecomastia). The syndrome may also cause reduced muscle mass, reduced body and facial hair, and enlarged breast tissue. Babies with Klinefelter syndrome typically have weak muscles, reduced strength, and quiet personalities. Klinefelter syndrome affects 1 in 500 to 1,000 newborn males. 7) Caster Semenya. There is a spectrum of the traits and you might have one or you might have all of them. It is estimated that 1 in every 500 may have the syndrome. Ways To Give; Our Donor Wall; Volunteer; Fundraising Campaigns ; Research Index; DONATE; Shop; Home Ryan Bregante 2020-08-18T09:34:14-07:00. The most important thing to remember is that KS has a very wide range of effects, the severity of which varies considerably from person to person. Objective To investigate the criminal pattern in men between 15 and 70 years of age diagnosed with 47,XXY (Klinefelter's syndrome (KS)) or 47,XYY compared to the general population. Frequency. If you would like to share your own story or your children’s story about being diagnosed with an X and Y variation please email Info@livingwithxxy.com . Father Learns of Son’s Xxy. PurposeKlinefelter’s syndrome (KS) is associated with specific neurobehavioral features and personality traits. The primary features are infertility and small poorly functioning testicles. Females have two X chromosomes (46,XX), and males have one X and one Y chromosome (46,XY). The effects of Klinefelter syndrome vary, and not everyone has the same signs and symptoms. Our Community, Pregnant Mothers Stories . They tend to be quiet, sensitive, and unassertive, but personality characteristics vary among affected individuals. Jun 4, 2019 - Klinefelter syndrome is a genetic disorder that affects males. the answer to this question is the same as if you asked me if i would ever date a dentist. If you have any further questions or concerns, please speak to the doctor or nurse caring for you. i dont no. Our Positive Traits. van Rijn S(1), Swaab H. Author information: (1)Leiden University, Clinical Child and Adolescent Studies, the Netherlands. We want to hear and share your story with the world. Klinefelter syndrome (KS), also known as 47,XXY is the set of symptoms that result from two or more X chromosomes in males. Klinefelter syndrome is a genetic abnormality that is common with males. On June 22, 2014, Isaiah had been diagnosed with Marfan syndrome. Klinefelter's syndrome (KS) is due to the presence of one or more supernumerary X chromosomes. Klinefelter syndrome is a sex chromosome disorder in boys and men that results from the presence of an extra X chromosome in cells. Having extra X chromosomes can cause a male to have some physical traits unusual for males. In most cases, the men with Klinefelter syndrome are infertile. If you have just received a diagnosis of Klinefelter’s Syndrome (KS) for your child or unborn baby you have come to the right place for reliable information and friendly support. The prevalence of Klinefelter syndrome is around one in every 500 or 1000 newborn males. If you are an adult diagnosed with Klinefelter’s Syndrome, please visit our adult area for information and advice about how Klinefelter’s Syndrome could affect you. Early studies reported disproportionate numbers of individuals with Klinefelter syndrome in the prison system, which led to the perception that Klinefelter syndrome was associated with criminality. Testosterone is a male hormone that usually stimulates sexual traits like body hair and muscle growth. They also can take longer to do things like sit up, crawl, walk, and speak. Reduced production of testosterone may cause several symptoms. Often, symptoms are subtle and subjects do not realize they are affected. There are lots of forms of testosterone out there depending on what country you live in. Aneuploidy 47,XXY is the most common abnormality of sex chromosomes in humans, with an incidence equal to 1/500 male live births. J Sex Med. Additionally, up to 1 in 4 children with Klinefelter syndrome are diagnosed with a psychiatric disturbance. She is a South African middle-distance runner and 2016 Olympic gold medalist. Here, we report high levels of schizophrenia-spectrum pathology in 32 men with this syndrome in comparison with 26 healthy controls. srijn@fsw.leidenuniv.nl AIM: Studying Klinefelter syndrome (KS) (47,XXY) can reveal insights into mechanisms of neurodevelopment. Between 1-400 to 1-650– Males are born with Klinefelter syndrome. It can affect physical and mental development. to me personally it is just a label and klinefelters does not define you. See more ideas about klinefelter syndrome, x chromosome, syndrome. Klinefelter syndrome is a genetic condition that affects males. Klinefelter syndrome happens when a male is born with an additional X chromosome. He can also have more fat in the belly region. We aimed to verify if 1 year-testosterone-replacement therapy could produce a psychopathological recovery and a satisfactory quality of life in Klinefelter syndrome (KS) patients compared to matched healthy controls. Donate Help the KSA, make a donation . Most males have one Y and one X chromosome. you have your own personality and traits some may be traits of the syndrome but as you said your self people with klinefelters are not all the same. I am one of them. This results in smaller-sized testicles, low testosterone levels, and possibly infertility. People typically have 46 chromosomes in each cell, two of which are the sex chromosomes. Case of Klinefelter’s syndrome in an 18 year old male presented with antisocial personality disorder September 2014 Dusunen Adam The Journal of Psychiatry and Neurological Sciences 27(3):254-256 What is Klinefelter Syndrome and why do I have it? Nearly 70 years after its description, Klinefelter syndrome (KS) remains a largely undiagnosed condition. Other traits that a boy that is suffering from Klinefelter’s syndrome can depict include smaller penis and testes, breast growth, less body and facial hair, wider hips and narrower shoulders, reduced tone of the muscles, weaker bones, lower energy and decreased interest in sex. XXY Baby is Born. Klinefelter syndrome occurs when a boy is born with one or more extra X chromosomes. Asking your doctor can be a hit or miss when understanding Klinefelter syndrome. 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